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Rotate the site every time, because injecting the same spot repeatedly can cause a fatty lump (lipohypertrophy) that slows absorption, a point the NHS is clear about when it advises you to rotate sites daily
5 Journal of Orthopaedic ResearchChang CH et al
CL Answer Does methylene blue increase energy, slow aging, or improve memory
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[12] Clinical manifestations, such as low blood pressure, and low-grade fevers, and dark circles around the eyes, may occur