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However, it can also be given slowly intravenously or subcutaneously (injected into a vein or under the skin)

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SURMOUNT-2, which included participants with type 2 diabetes, showed weight reductions of 12.8% to 15.7% with tirzepatide versus 3.2% with placebo

Importantly, the differences in Ex4 and P5 in vivo efficacy are not due to differences in peptide pharmacokinetics as both peptides display similar half-life in mouse serum (supplementary Fig