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Astaxanthin also attenuates the increase in CHOP and ER chaperone protein via the MAPK pathway and inhibits the influx of calcium ions (Grimmig et al., 2019) and upregulates HO-1 via the ERK1/2 pathway to protect against the neurotoxicity of A (Lin et al., 2017)

& Heinecke, J

Further dermoscopic examination was done for follow-up during and after treatment

It disrupts the copper chaperone system (e.g., COX17, SCO1/SCO2), drastically reducing CCO biosynthesis and activity

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