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As a result, they might experience a more noticeable decline in body weight

Non-alcoholic fatty liver disease (NAFLD) affects approximately 25% of adults and can progress to serious liver damage

doi: 10.1016/j.jpba.2006.04.002 79 HordieiKGontovaTTrumbeckaiteSYaremenkoMRaudoneL

2.4 Switching Between RYBELSUS (Formulations R1 or R2) or from OZEMPIC to RYBELSUS Switching Between RYBELSUS Formulations Do not switch between RYBELSUS formulations during the initiation phase (Days 1-30) [see Dosage and Administration (2.3)]

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A limitation of this study is that the weight loss in the RETA group could not be matched simply by restricting food intake due to the many pathways targeted by RETA leading to, for example, significantly elevated cecal content indicative of reduced gastric motility