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Next, the effectiveness of NP4 in activating the immune response in mice in orthotopic K7M2 osteosarcoma models was further investigated
The serine de novo synthesis pathway (SSP) represents a pivotal metabolic bypass of glycolytic metabolism, whereby the glycolytic intermediate 3-phosphoglyceric acid is converted into serine and glycine through the action of numerous metabolic enzymes, including phosphoglycerate dehydrogenase (PHGDH)