In addition, Akt phosphorylates Bcl2 to promote cell survival and inactivates p27 and Bad to inhibit cell cycle arrest and apoptosis
[DOI] [PMC free article] [PubMed] [Google Scholar] Lee EB, Fleischmann R, Hall S, Wilkinson B, Bradley JD, Gruben D, Koncz T, Krishnaswami S, Wallenstein GV, Zang C, Zwillich SH, van Vollenhoven RF
Yes, this is an important marker for sure but there are many others
A synaptic amplifier of hunger for regaining body weight in the hypothalamus
Histologic evidence from massive weight loss demonstrates increased elastic fiber density compared to morbidly obese skin, but altered collagen architecture and decreased dermal thickness are common, which can translate to visible laxity even if elastic fibers are on the rise
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