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While these medications don't directly damage eye structures, clinical evidence shows they may worsen diabetic retinopathy in specific circumstancesparticularly when patients with pre-existing retinal disease experience rapid blood sugar improvements

Protein glutathiolation by nitric oxide: an intracellular mechanism regulating redox protein modification

British Journal of Pharmacology , 179(4), 557570

Use a sterile injection technique to avoid infection and follow the dosage instructions closely to prevent overuse

That same 0.25mg dose from a 2.5mg/ml solution requires 10 units

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