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doi:10.1111/j.1600-0749.1992.tb00540.x

Food and Drug Administration classifies the sweetener as generally recognized as safe." Overall, the evidence supports allulose as well tolerated and metabolically safe in typical dietary use, Dr

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However, several melanocortin agonists demonstrated activation of central MC receptors or penetration into the CNS without noted cardiac side effects (25, 98, 102)