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[DOI] [PubMed] [Google Scholar] 61.Rahal J.P., Malek A.M., Heilman C.B

While GWAS studies have identified SNPs in gene loci that play roles in classical hypertension mechanisms (such as vasoconstriction, sodium reabsorption, and sympathetic nervous system activity), the identified gene loci also relate to inflammation and immunity

doi: 10.1016/j.bbi.2024.03.019 136

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These links reflect shared immunogenetic factors, including IL-18, IFN-, CTLA-4, HLA-DQ8, HLA-DQ2, HLA-B8, and HLA-DR3, many of which are integral to antigen presentation within the major histocompatibility complex (MHC)

5-Amino-1MQ is an investigational, research-use-only compound