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Endocrinology 146 : 26022609 Yakar S et al

TMAO is mainly derived from gut, where the gut microbiota converts TMA precursors into TMA, which is absorbed into the bloodstream through the intestinal mucosa, and then transformed into TMAO by hepatic flavin monooxygenases (FMOs) in the liver

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Understanding when and why this happens helps you prepare and manage the adjustment period effectively

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Localized redness, itching, swelling, or mild discomfort at injection sites typically occur as mild to moderate reactions that resolve within days