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279 In preclinical studies, GLP-1 RAs reduce amyloid- deposition, attenuate tau phosphorylation, and suppress microglial activation

Stromal stiffness-regulated IGF2BP2 in pancreatic cancer drives immune evasion via sphingomyelin metabolism

Journal of Rheumatology

This distinction is crucial when comparing these findings with clinical trials involving patients with established symptomatic disease

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Adv Nutr 6(1):6472 Steane SE, Cuffe JS, Moritz KM (2023) The role of maternal choline, folate and one-carbon metabolism in mediating the impact of prenatal alcohol exposure on placental and fetal development