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Results are typically reported after 612 weeks
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In a DSS-induced colitis model, piperine administration increased the levels of Lactobacillus and Bifidobacterium , decreased Enterobacteriaceae , and improved colonic histopathology
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However, even larger PET MPs (median diameter 85 m) may pose a risk to renal function, as a single oral exposure led to increased serum urea and creatinine levels in Wistar rats [149]
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