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Despite the BBB acting as a restrictive barrier, endothelial cells participate in mediating inflammation in the brain by communicating immunological signals to perivascular Ms and neighboring microglia, which can extend to parenchymal cells

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This reveals great variability in sample size derived from various methodological designs

Observational data suggest a notable under-utilisation of GLP-1 RAs among individuals in lower socioeconomic groups, primarily due to the high cost of these medications, highlighting the disparity in access to effective diabetes treatments based on socioeconomic factors [63]