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For one, they point out that prior to its 2017 FDA approval, semaglutide was rigorously studied in multiple randomized controlled trials around the world

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These drugs have also caused new or worsening kidney disease, including kidney failure, in some people

Discussion Summary of findings In the present study, we found that the risk of MOF was slightly lower, albeit not significantly, in those treated with GLP-1 RA compared to those treated with DPP-4is as add-on therapies to metformin

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