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Isotretinoin Isotretinoin: Examination and Clinical Applications Overview Isotretinoin is a systemic retinoid medication derived from vitamin A, used primarily to treat severe or refractory acne, but with broader implications for epithelialcell differentiation, sebum regulation, and inflammatorysignaling pathways

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How It Works It promotes the formation of new blood vessels (angiogenesis), upregulates growth factor receptors, and activates multiple healing pathways

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