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Given the role of angiogenesis in the growth and/or maintenance of neurovascular units in the nervous system, a role for abnormal angiogenesis in neurodegenerative diseases has been hypothesized and aberrant angiogenesis has been proposed as a potential factor in the progression of neurodegenerative diseases (Parkes et al
Glucagon and energy expenditure
Cardiovascular disease and risk management: standards of care in diabetes-2024
Importantly, there is an absence of data demonstrating development of chronic pancreatitis in humans treated with GLP-1RAs to support this connection
If a modest rise in heart rate were clinically harmful, outcome trials would likely show increased event rates
BPC-157 is a naturally occurring peptide fragment it can't be strongly patented, so the economic incentive for $100M+ clinical trials doesn't exist
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