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the skeletal muscles of non-exercised mice did not show significant alterations in response to MOTS-c (Supplementary Fig

67 , e12611 (2019)

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For example, a 2014 study published in Dermatology Practical & Conceptual found that both oral and topical forms of Glutathione resulted in a reduction in skin melanin content, but the study concluded that more extensive research is needed to verify these effects across broader populations

While these functional improvements occurred in animal models, they suggest possible benefits for mobility and quality of life that would need confirmation in human trials

doi: 10.1001/jama.2016.0287 2