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The gluconate part is there to promote the bioavailability of copper and it also plays a role in cellular regeneration (involved in the synthesis of ribose sugars, structural components of DNA and RNA)

24,65 However, Schmorls nodes may have different aetiologies, and cause-response in relation to disc degeneration remains a question of debate

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Some studies on microbial models have shown that disruption of the Trx system can independently cause a disruption in homeostatic redox control or stress responses (Arner and Holmgren, 2000

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