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Pharmaceuticals Memorable moments in 2023 The moments, numbers, and news that the C&EN team found noteworthy this year by Laura Howes Open-source drug discovery prepared for the next pandemic New antiviral drug leads were reported by an open-source drug discovery effort, the COVID Moonshot Consortium ( Science 2023, DOI: 10.1126/science.abo7201)

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At 0.5mg: 10 doses

Retrieved from Jensterle, M., Rizzo, M., Haluzk, M., et al

In prospective data, 87% tolerated the transition without significant GI symptoms and only 2% discontinued