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Previously, a Phase 3 clinical trial for the amustaline/glutathione (GSH) PR system was halted when antibodies specific to acridine (a by-product of amustaline) were found in patients

Olthof et al., 2016), and betaine could reduce the increase in Hcy after methionine level has been increased to 50% (Olthof and Verhoef, 2005)

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L-carnitine may help increase mitochondrial function, which plays a key role in disease and healthy aging