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Therefore, the function of system Xc- has a direct impact on GSH level and GPX4 activity ( 1.2 The pathway of ferroptosis 1.2.1 GSH-GPX4 pathway The fundamental cause of ferroptosis is the imbalance of redox balance between oxidant and antioxidant, which is driven by the abnormal expression and activity of various redox enzymes in the process of producing free radicals and lipid oxidation products or detoxification
Molecular Biology of Glutathione Peroxidase 4: From Genomic Structure to Developmental Expression and Neural Function. Biological Chemistry 388: 10071017
mu-Opioid receptor desensitization: homologous or heterologous
Nephron Physiol (2014) 128(1-2):17
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