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Magnetic resonance-based techniques have gained greater translational relevance because they can be integrated into standard clinical imaging platforms without ionising radiation
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The conditions that have been associated with glutathione deficiency include the following: Neurodegenerative diseases such as Alzheimers, Parkinsons and Huntingtons disease and ALS Pulmonary diseases such as COPD, asthma, and acute respiratory distress syndrome Immune system disorders Cardiovascular diseases such as high blood pressure, elevated cholesterol, and heart attacks Chronic age-related disorders such as cataracts, macular degeneration, hearing impairment, and glaucoma Liver disease Cystic fibrosis Aging processes (Pizzorno, 2014)
Renal tubular epithelial-specific deletion of PRMT1 mice were generated by crossing floxed PRMT1 mice with Cdh16-Cre mice and wild-type littermates were used as controls
& Perna, A
