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Serum opioid peptide concentration was 1.6-fold significantly higher in children with ASD ( p : Rueda-Ruzafa L, Cruz F, Cardona D, Hone AJ, Molina-Torres G, Snchez-Labraca N, Roman P (2020) Opioid system influences gut-brain axis: dysbiosis and related alterations

Heterozygous carriers or minors with one copy of the thalassemia trait gene have no symptoms whereas a child/adult with homozygous thalassemia will present with the disease

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Vegetarians, vegans, and people who eat little animal protein may fall short

It does not affect insulin or IGF-1 levels and is well tolerated by most patients