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GSH levels in blood increased after 1, 3, and 6 months versus baseline

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120,121 Chromatin immunoprecipitation and transcriptomic analyses have identified TFEB as a transcriptional activator of autophagosome formation genes ( MAP1LC3B, ATG5 , and ATG7 ), lysosomal membrane and hydrolase genes ( LAMP1, CTSA , and CTSD ), and fusion-related SNARE components ( STX17 and VAMP8 )