Of note, 4-hydroxynonenal (4-HNE), as the end-product of lipid peroxidation, could increase the expression of Fas in a concentration- and time-dependent manner, accompanied by the activation of caspase 3 and finally leading to apoptosis [83]
Glutathione serves as a potent antioxidant eliminating reactive oxygen species (ROS) such as hydroxy radicals, peroxynitrites, and hydroperoxides
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Severe asthma with fungal sensitization (SAFS) is a recognized clinical entity in which patients have markedly poorer outcomes than non-sensitized asthmatics
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Molina-Holgado et al., 2022)