Acknowledgements The infrastructure for the NESDA study ( is funded through the Geestkracht program of the Netherlands Organisation for Health Research and Development (ZonMw, grant number 10-000-1002) and financial contributions by participating universities and mental health care organizations (VU University Medical Center, GGZ inGeest, Leiden University Medical Center, Leiden University, GGZ Rivierduinen, University Medical Center Groningen, University of Groningen, Lentis, GGZ Friesland, GGZ Drenthe, Rob Giel Onderzoekscentrum)
Do not take before sleep
The preserved pulsatile GH pattern maintains physiological signaling that optimizes tissue repair without the complications associated with continuous hormone elevation
Placement of an intracranial monitor to guide ICP therapy is risky because of concomitant coagulopathy and remains controversial
An important limitation of the available RCTs is the lack of standardization in supplement dosing and the variable bioavailability of these compounds, which May contribute to the heterogeneity of clinical outcomes
For proper reconstitution technique across all peptides, consistent gentle mixing is the universal rule
