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To exclude any potential effects of exendin 939 on insulin secretion via GLP-1R interaction, we analyzed key protein sequences involved in TRPV1 inhibition

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J Biol Chem 284:90599065 Han L, Hiratake J, Kamiyama A, Sakata K (2007) Design, synthesis, and evaluation of gamma-phosphono diester analogues of glutamate as highly potent inhibitors and active site probes of gamma-glutamyl transpeptidase