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Metabolic Disturbances One of the primary concerns, according to Roberts, involves metabolic disturbances

Of these, myo-inositol and D-chiro-inositol are among the most abundant biologically active forms

4.2 Reduced glucotoxicity and lipotoxicity Glucotoxicity is characterized by irreversible tissue and cell damage resulting from insulin resistance and persistently elevated glucose levels stemming from excessive carbohydrate intake (Mota et al., 2016)