Erastin and RSL3 are two well-known compounds that induce ferroptosis ( via System Xc and to inhibit GPX4, respectively ( Figure 1 )
doi: 10.3389/fphar.2025.1602976 Received 30 March 2025 Revised 13 November 2025 Accepted 14 November 2025 Published 19 December 2025 Volume 16 - 2025 Edited by Bernd Rosenkranz, Fundisa African Academy of Medicines Development, South Africa Reviewed by Kacper Nijakowski, Poznan University of Medical Sciences, Poland Miriam Njoki Karinja, Science for Africa Foundation, Kenya Updates Copyright 2025 Mazur, Ndokaj, Salerno, Vallone, Ardan, Bietolini, Carrouel, Wilk, Sarig, Ottolenghi and Bourgeois
Technique tips that most guides miss A hot drink 10 to 15 minutes before administration increases blood flow to the sublingual region, which can enhance absorption rate
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