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10.1016/s0028-3908(01)00175-7 82 HerbertJ

What if a medication designed to lower blood sugar could also help protect the brain

Bioavailabilitythe percentage of medication that reaches your bloodstreamis lower with oral formulations due to stomach acid degradation and first-pass liver metabolism

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Moreover, the current breakthroughs in the treatment of psychosis have renewed interest in evaluating new drugs acting through these pathways