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A common pattern involves using nasal spray for TB-500 systemic delivery while injecting BPC-157 locally at specific injury sites

Primary endpoint: composite MACE (cardiovascular death, non-fatal myocardial infarction, non-fatal stroke)

They provide strong proof that a compound has a direct biological effect on the target tissue, but they cannot tell us how that compound will behave when applied to human skin (where absorption, distribution, and metabolism add complexity)

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