Common reasons for deficiency include: Low intake particularly diets low in whole grains, legumes, leafy greens or animal products Gut health issues like low stomach acid, SIBO, coeliac disease, IBD, or other factors affecting absorption Medications such as the contraceptive pill, metformin or antacids, which can deplete B vitamins Chronic stress increases demand for certain b vitamins, including B5 and B6 Vegan or vegetarian diets higher risk of B12 deficiency, which can be corrected through supplementation Genetic reasons some mutations on certain genes can increase a persons need for B vitamins This is why I always recommend testing before supplementing
After age 35 you start losing some melanocytes, and the loss of melanocytes accelerates after age 50
STORAGE Lyophilized powder: 20C long-term, 28C short-term
Peptide injections intimidate most beginners
TRPC6 is also expressed in these erythrocytic progenitor cells [99], and in humans, erythrocytes TRPC6 accomplishes Ca 2+ influx [100] in contrast to mouse erythrocytes, where TRPC4/5 are involved [101]
This dietary pattern change may contribute to declining b12 levels as much as or more than any absorption issue