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The Schizophrenia phenotype in 22q11 deletion syndrome

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It typically appears within 24 to 72 hours of an injection and diminishes over the following days

( i ) Fasting plasma GIP (n = 5 per group), ( j ) total GLP-1 (CON n = 9, Gipr AP-KO n = 8), ( k ) insulin (CON n = 5, GIPR AP-KO n = 4), (l) food intake post IPGTT (CON n = 6, Gipr AP-KO n = 6), ( m ) ad lib fed blood glucose (CON n = 6, Gipr AP-KO n = 6), (n) RER (time x group F(24, 168) = 1.739 p = 0.023), ( o ) energy expenditure (with ANCOVA using BW as covariate), ( p ) ambulatory activity (x beam breaks)

Distress is a potentially harmful oxidative stress that causes neuroinflammation and disrupts the astrocyte-neuron connection, leading to ASD [121-123]

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