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In turn, the QMP substitutions improved the PK properties of a recombinant version of the GLP-1 albumin fusion albiglutide, irrespective of the presence of L585

Therefore, this underscores an urgent need for alternative therapeutic strategies and a deeper understanding of DMEDs pathophysiology

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The key MMPs that participate in the degradation of ECM are MMP-1, -2, -3, -9, and -13, demonstrated by animal models, and chondrocytes taken from OA-affected patients [911]

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