All statistical tests were two-tailed and a p-value less than 0.05 was considered statistically significant
Glucagon-like peptide-1 (GLP-1) is a naturally occurring hormone in the body that plays a role in regulating blood sugar, appetite, and digestion
Apply the legitimacy checklist in this article
How does a 7 year old accidently take an injection? someone asked
Why this trial matters: First triple hormone receptor agonist showing major Phase III weight-loss efficacy Delivers weight-loss outcomes far beyond many current therapies Suggests a potential new metabolic and obesity care benchmark Semaglutide Shows Consistent Liver Benefits in MASH In the Phase III ESSENCE study, once-weekly semaglutide 2.4 mg significantly increased rates of steatohepatitis resolution and fibrosis improvement on liver biopsy in adults with metabolic dysfunction-associated steatohepatitis (MASH), compared with placebo
Shekhar, C., Khosya, R., Thakur, K., et al (2024)