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Abstract Melanotic neuroectodermal tumor of infancy (MNTI) is a rare benign neoplasm that can be mistaken for malignancies due to its unfamiliarity among clinicians and aggressive clinical appearance

Historically, neuropathy endpoints were not primary outcomes in major diabetes trials

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Rarely, some have reported cramping or abdominal discomfort.These tend to be transient

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However, some clinicians may consider this approach in specific scenarios: patients who achieve substantial weight loss and demonstrate exceptional adherence to lifestyle modifications, those using the medication as a bridge to bariatric surgery, or individuals who experience intolerable side effects but gained valuable time to establish healthier habits