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Headline Numbers Intention-to-treat 3-point MACE: semaglutide associated with 29% lower risk versus tirzepatide (statistically significant) Intention-to-treat 5-point MACE: semaglutide associated with 22% lower risk (statistically significant) Per-protocol 3-point MACE: 57% lower risk for semaglutide Per-protocol 5-point MACE: 43% lower risk for semaglutide Absolute event rates: 0.1% (15 events) on semaglutide vs 0.4% (39 events) on tirzepatide The per-protocol numbers count only patients who actually stayed on their assigned drug