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(2024) real-world study, adverse events were reported more often with oral semaglutide (16.7%) than with injectable semaglutide (4.9%), and discontinuation due to side effects was also more common in the oral group

Cajochen C, Krauchi K, Wirz-Justice A

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The nasal spray delivery format may increase systemic absorption risk relative to lyophilized powder due to faster potential uptake via the intranasal route

doi: 10.1080/09553002.2019.1642535 110 SongK