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Semaglutide typically does not directly alter hormones that control your menstrual cycle, but rapid weight loss from the medication can trigger temporary changes in period timing, flow, or regularityespecially in the first few months of treatment

Neuroprotective efficacy of the peroxisome proliferator-activated receptor -selective agonists in vitro and in vivo

However, high doses may cause side effects such as nausea, vomiting, diarrhea, and constipation

Its been suggested that tirzepatides had a greater impact on the absorption of oral hormonal contraceptives than semaglutides

The study was conducted over a one year period

These challenges lead many to ask if compounded semaglutide is a comparable alternative