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Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment

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LB0005 orelabrutinib, an irreversible inhibitor of brutons tyrosine kinase (BTK), for the treatment of systemic lupus erythematosus (SLE): results of a randomized, double-blind, placebo-controlled, phase Ib/IIa dose-finding study

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However, SKO hyperglycaemia was significantly lowered by liraglutide treatment with both male and female SKO mice displaying a ~35% reduction in blood glucose concentrations ( Figure 2G )