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I., Gefen, A., et al

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As a GLP-1 receptor agonist, it stimulates the pancreas to produce insulin when blood sugar is high and inhibits glucose release from the liver when levels are low helping maintain stable blood sugar levels essential for managing diabetes

doi: 10.5435/JAAOSGlobal-D-25- 6: Mayfield CK, Bolia IK, Feingold CL, Lin EH, Liu JN, Rick Hatch GF, Gamradt SC, Weber AE

Because semaglutide and tirzepatide affect blood glucose levels and cardiovascular function, most donation centers classify them as medications requiring medical review before donation eligibility can be determined

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