Chemokine CCL2 and Its Receptor CCR2 in Regulation of Cognitive Functions and in Development of Aging Diseases
Fig ure 2 Microscopic presentation of intestinal adaptation in diclofenac-treated animals
Bioorganic & Medicinal Chemistry, 26 (10), 27002707
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This review presented fundamental information regarding two categories of GLP-1 receptor agonists (GLP-1RAs): peptide-based and small molecule compounds, and elaborated their potential neuroprotective effects by inhibiting neuroinflammation, reducing neuronal apoptosis, and ultimately improving cognitive function in various neurodegenerative diseases
Those include Ozempic and its sister drug approved for obesity, Wegovy, which use semaglutide, and Mounjaro and Zepbound, for diabetes and obesity, respectively, which use the active ingredient tirzepatide