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Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study PMID: 8637402 Life Sci

Both share the GLP-1 class side-effect profile, led by gastrointestinal symptoms: nausea, vomiting, diarrhea, and constipation, worst during dose increases

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This improvement is partly attributed to its stimulant-like effects, which can be particularly beneficial for individuals experiencing the lethargy and fatigue often associated with depression

To test this, GSH concentrations in various tissues were determined in young, mature and old mice throughout a 24-hr time course after acute EtOH treatment, and after increasing doses of EtOH