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Recently, a methodology termed selective organ targeting (SORT) has been developed, which enables controllable delivery of nucleic acids to target tissues [65]

Supplementary information The spectrophotometer is set at a 412-nm wavelength and a continuous reading is performed for a few minutes until a plateau is reached

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Whether a 50mg tablet will receive a UK licence depends on further regulatory review and clinical guidance there is no confirmed timeline

The magnitude of heart rate increase observed in the Phase 2 trial varied by dose