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Sodium butyrate can be produced in the gut and is well known for shaping the microbiome [37] and as an important metabolite for gut-brain-axis signaling [37, 38]
Moreover, in previous studies by our group, chlorophyllin has been shown to inhibit the GSTP1 enzyme, which demonstrates it may potentially increase the efficacy of chemotherapy by suppressing drug resistance (Musdal et al
[77] A 2022 review noted a prevalence between 5% and 18%
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ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
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