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Maniaci, C

Multiple studies have demonstrated that GLP-1RAs promote the polarization of uncommitted macrophages toward an anti-inflammatory phenotype (127,128) and facilitate the transition from M1 to M2 polarization (129,130)

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At the time of writing, neither cagrilintide nor retatrutide has received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA) for use in the United Kingdom

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Additionally, intestinal epithelial cells can import intact GSH from the lumen via specific plasma membrane transporters (7)