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The trials were originally met with limited enthusiasm since several extensive outcome trials had indicated that intensified diabetes therapy was not associated with cardiovascular benefit
Clin Exp Dermatol
Pharmaceutical development is accelerating, particularly in the oral small molecule classdrugs that come in pill form, can be taken daily, and work with high target specificity (big intended effects, minimal side effects)
The inhibited kinase is glycogen synthase kinase 3 (GSK3)
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doi: 10.1111/tmi.13598 [DOI] [PubMed] [Google Scholar] 294
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