Clinical trials published in the Journal of the American Medical Association (JAMA) also showed improvements in blood pressure and cholesterol levels in some patients (source)
I Carefully Researched Compounding Pharmacies I was well aware from reading all the news that not all compounding pharmacies are created equal
Practical Implementation and Professional Guidance Dosing and Timing Guidelines When incorporating creatine into a GLP-1 medication regimen, proper dosing and timing are essential: Standard Protocol: Daily Dose : 3-5 grams of creatine monohydrate Timing : Can be taken at any time of day for convenience Loading Phase : Optional 20g daily for 5 days (divided into 4 doses) Duration : Can be taken continuously without cycling Optimal Timing Options: Post-Workout With a small amount of carbohydrates to enhance uptake Morning Routine Consistent daily timing for habit formation With Meals May reduce potential digestive upset in sensitive individuals Managing Expectations and Monitoring Progress Creatine initially causes a 2-4 pound increase in body weight due to increased water retention within muscle cells
If you consistently hit 1.2-1.6 grams per kilogram of body weight daily, you are in the protective range
One indirect consideration worth mentioning: creatine causes water retention within muscle cells, which can show up as a modest increase on the scale, typically one to three pounds in the first week or two of supplementation
This helps to buy you the time and headspace to understand why your body may have struggled to lose weight previously, and to build new long-term healthy habits
