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Aug 2015;241(2):649-56

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In ob/ob mice, increased human CRP, from continuous infusion or transgene expression, attenuated the physiological actions of exogenous leptin on food intake, body weight, blood glucose and lipid metabolism (9)

Clinical studies show impressive results, with people losing an average of 13% of their body weight over about 14 months

Compatibility studies generally use preservativefree formulations to maintain stability and particle size, which are critical for medication effectiveness