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5ac) and showed no significant changes in glucose tolerance after 16 weeks of HFD (Fig
WASHINGTON New findings from multiple studies demonstrate that glucagon-like peptide-1 receptor agonists (GLP-1RAs), a class of medications used to treat type 2 diabetes, play a significant role in improving cardiovascular outcomes like heart failure (HF), acute myocardial infarction (AMI), peripheral artery disease (PAD), and ST-elevation myocardial infarction (STEMI)
Acute phase peptides (BPC-157, Pinealon) that address immediate neuroprotection and excitotoxicity could be started first
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Discussion The results of the current meta-analysis, that included 60,080 patients with T2DM, 14,804 of whom without established CV disease, demonstrate that GLP-1RA reduce the risk of MACE by 14% in the overall diabetic population, with an apparently greater effect in patients with known CV disease as compared with those without established CV disease (16% vs 6% reduction, respectively)
